It’s been 10 years since Grey’s Anatomy pulled off one of its saddest character deaths ever. In Season 12, Wilmer Valderrama guest-starred in a handful of episodes as Kyle Diaz, a guitarist whose MS-related hand tremors brought him to the hospital for treatment.

One of his doctors was Stephanie Edwards (Jerrika Hinton), and she grew close to him as he underwent a deep-brain stimulation procedure by Amelia Shepherd (Caterina Scorsone). Memorably, Kyle’s surgery required him to play the guitar during the operation so they could monitor for brain bleeds along the way.

Originally published on tvinsider.com, part of the BLOX Digital Content Exchange.

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