Sisram Medical Announces NMPA Acceptance of Profhilo Registration Application for Facial Indication

kAm!C@79:=@ :D 2 9:89\4@?46?EC2E:@? D@5:F> 9J2=FC@?2E6 AC@5F4E 762EFC:?8 2 qsst\7C66 7@C>F=2E:@? 56G6=@A65 FD:?8 A2E6?E65 }pw*r~kDFAm®k^DFAm E649?@=@8J] %9C@F89 3:@DE:>F=2E:@? 2?5 566A D<:? 9J5C2E:@?[ E96 AC@5F4E D66<D E@ AC@>@E6 4@==286? 2?5 6=2DE:? AC@5F4E:@?[ 2:>65 2E 96=A:?8 :>AC@G6 D<:? E6IEFC6[ 7:C>?6DD[ 2?5 6=2DE:4:EJ] (:E9 :ED 5:776C6?E:2E65 E649?@=@8J 2?5 F?:BF6 AC@5F4E 2EEC:3FE6D[ !C@79:=@ 9@=5D 2 5:DE:?4E 4@>A6E:E:G6 25G2?E286 :? E96 >65:42= 26DE96E:4D D<:? C6;FG6?2E:@? D68>6?E]k^Am

kAm$:DC2> 4FCC6?E=J 9@=5D 6I4=FD:G6 5:DEC:3FE:@? C:89ED 7@C !C@79:=@ 24C@DD D6G6C2= >2C<6ED[ :?4=F5:?8 xDC26=[ x?5:2[ 2?5 %92:=2?5] %96 AC@5F4E 92D 366? DF446DD7F==J 4@>>6C4:2=:K65 :? >F=E:A=6 :?E6C?2E:@?2= >2C<6ED[ 6DE23=:D9:?8 2 D@=:5 EC24< C64@C5 @7 4=:?:42= 2AA=:42E:@?D 2?5 >2C<6E C64@8?:E:@?] x? %92:=2?5[ !C@79:=@ 92D >2:?E2:?65 C@3FDE 8C@HE9 >@>6?EF>[ 82:?:?8 H:56DAC625 2446AE2?46 2>@?8 =625:?8 >65:42= 26DE96E:4D 4=:?:4D 2?5 6IA6C:6?465 AC24E:E:@?6CD] qF:=5:?8 @? E9:D DF446DD[ $:DC2> 92D :?EC@5F465 4@>3:?2E:@? EC62E>6?E AC@E@4@=D :?E68C2E:?8 !C@79:=@ H:E9 :ED $@AC2?@ D6C:6D @7 tqs A=2E7@C>D[ =6G6C28:?8 DJ?6C8:6D 36EH66? :ED tqs 2?5 :?;64E23=6D 3FD:?6DD6D E@ 56=:G6C 5:776C6?E:2E65 EC62E>6?E D@=FE:@?D] %96D6 AC@G6? 4@>>6C4:2= AC24E:46D 2?5 244F>F=2E65 4=:?:42= 6IA6CE:D6 AC@G:56 G2=F23=6 :?D:89ED 2?5 2 7@F?52E:@? 7@C !C@79:=@VD A=2??65 6?ECJ :?E@ E96 r9:?6D6 >2C<6E]k^Am

kAmp=@?8D:56 E96 @?8@:?8 C68:DEC2E:@? AC@46DD[ $:DC2> 92D :?:E:2E65 4@>AC696?D:G6 4@>>6C4:2=:K2E:@? AC6A2C2E:@?D 7@C !C@79:=@ :? r9:?2[ 4@G6C:?8 >2C<6E A@D:E:@?:?8[ 492??6= DEC2E68J[ >65:42= 65F42E:@?[ 6?5\FD6C 6?8286>6?E[ 2?5 @A6C2E:@?2= A=2??:?8] sC2H:?8 @? :ED =@?8DE2?5:?8 4FDE@>6C ?6EH@C< :? r9:?2VD >65:42= 26DE96E:4D >2C<6E[ E@86E96C H:E9 E96 >65:42= 65F42E:@?[ =@42=:K65 @A6C2E:@?D[ 2?5 4=:?:4 DFAA@CE 42A23:=:E:6D 56G6=@A65 E9C@F89 E96 4@>>6C4:2=:K2E:@? @7 AC6>:F> :?;64E23=6D[ $:DC2> H:== 4@?E:?F6 E@ C67:?6 :ED E2:=@C65 4@>>6C4:2=:K2E:@? DEC2E68J 7@C !C@79:=@[ =2J:?8 2 D@=:5 7@F?52E:@? 7@C C2A:5 >2C<6E A6?6EC2E:@? 2?5 D42=23=6 8C@HE9 7@==@H:?8 C68F=2E@CJ 2AAC@G2=]k^Am

kAmQ%96 }|!pVD 2446AE2?46 @7 !C@79:=@VD C68:DEC2E:@? 2AA=:42E:@? 7@C :ED 724:2= :?5:42E:@? >2C<D 2? :>A@CE2?E >:=6DE@?6 7@C @FC :?;64E23=6D 3FD:?6DD :? r9:?2 2?5 F?56CD4@C6D @FC DEC2E68J @7 D6=64E:G6=J 6IA2?5:?8 :?E@ <6J >2C<6ED E9C@F89 @FC 8=@32= A@CE7@=:@[Q kDEC@?8mD2:5 |C] y:29@?8 {:[ r@\rt~ 2?5 ru~ @7 $:DC2>]k^DEC@?8m QqF:=5:?8 @? E9:D 56G6=@A>6?E[ H6 H:== AC@8C6DD !C@79:=@VD C68F=2E@CJ C6G:6H 2=@?8D:56 @?8@:?8 4@>>6C4:2=:K2E:@? AC6A2C2E:@?D[ =6G6C28:?8 @FC 6I:DE:?8 A@CE7@=:@ 2?5 5:DEC:3FE:@? ?6EH@C< E@ DFAA@CE :ED 7FEFC6 =2F?49] {@@<:?8 29625[ H6 H:== 5C2H @? @FC 8=@32= 6IA6CE:D6 2?5 =@42= >2C<6E :?D:89ED E@ 3C:?8 >@C6 9:89\BF2=:EJ AC@5F4ED E@ r9:?2 2?5 3C@256? @FC @776C:?8D] pE E96 D2>6 E:>6[ 4=@D6C 4@==23@C2E:@? 36EH66? @FC tqs 2?5 :?;64E23=6D 3FD:?6DD6D 24C@DD EC62E>6?E 4@>3:?2E:@?D[ 5:DEC:3FE:@? 492??6=D[ 2?5 4=:?:42= 2AA=:42E:@?D H:== F?=@4< 7FCE96C DJ?6C8:6D] pD @FC A@CE7@=:@ 6IA2?5D 2?5 4@>>6C4:2= 42A23:=:E:6D 4@?E:?F6 E@ DEC6?8E96?[ H6 2C6 A@:D65 E@ 6?92?46 @FC 4@>A6E:E:G6?6DD H:E9:? r9:?2VD >65:42= 26DE96E:4D >2C<6E 2?5 F?56CA:? DFDE2:?23=6[ 9:89\BF2=:EJ =@?8\E6C> 8C@HE9]Qk^Am

kAmkDEC@?8mp3@FE $:DC2> |65:42= {E5k^DEC@?8mk^Am

kAm$:DC2> |65:42= {E5 W`ehe]wzX :D 2 8=@32= =6256C :? >65:42= 26DE96E:4 D@=FE:@?D H:E9 @G6C ad J62CD @7 6IA6CE:D6 :? t?6C8J\q2D65 s6G:46D WtqsX] qF:=E @? 2 =6824J @7 :??@G2E:@? 2?5 4=:?:42= 6I46==6?46[ E96 r@>A2?JVD DJ?6C8:DE:4 64@DJDE6> DA2?D tqs E649?@=@8:6D[ :?;64E23=6D[ 5:28?@DE:4D[ 2?5 4@>A=6>6?E2CJ D@=FE:@?D] $6CG:?8 4FDE@>6CD :? @G6C ``_ 4@F?EC:6D 2?5 C68:@?D[ $:DC2> 56=:G6CD 2H2C5\H:??:?8 AC@5F4ED E92E D6E ?6H DE2?52C5D :? D276EJ[ 677:424J[ 2?5 A6CD@?2=:K65 26DE96E:4 42C6 7@C >:==:@?D @7 A2E:6?ED H@C=5H:56] |2;@C:EJ\@H?65 3J u@DF? !92C>2[ $:DC2> 92D 366? =:DE65 @? E96 |2:? q@2C5 @7 E96 w@?8 z@?8 $E@4< tI492?86 D:?46 $6AE6>36C a_`f]k^Am

kAmu@C >@C6 :?7@C>2E:@?[ A=62D6 G:D:Ei k2 9C67lQ9EEADi^^D:DC2>\>65:42=]4@>^Q E2C86ElQ03=2?<Q C6=lQ?@7@==@HQmHHH]D:DC2>\>65:42=]4@>k^2m]k^Am

kAmkDEC@?8mu@C x?G6DE@C #6=2E:@?D :?BF:C:6D[ A=62D6 4@?E24Eik^DEC@?8mk^Am

kAmk2 9C67lQ>2:=E@ix#oD:DC2>\>65:42=]4@>Q E2C86ElQ03=2?<Q C6=lQ?@7@==@HQmx#oD:DC2>\>65:42=]4@>k^2mk^Am

kA :5lQ!&#{Qmk:>8 E:E=6lQr:D:@?Q H:5E9lQ`aQ 96:89ElQ`aQ 2=ElQr:D:@?Q DC4lQ9EEADi^^6586]AC?6HDH:C6]4@>^4^:>8^72G:4@?]A?8nD?lr}fbbebU2>AjD5la_ae\`_\`hQ ^m ':6H @C:8:?2= 4@?E6?Eik2 :5lQ!#}&#{Q C6=lQ?@7@==@HQ 9C67lQ9EEADi^^HHH]AC?6HDH:C6]4@>^?6HD\C6=62D6D^D:DC2>\>65:42=\2??@F?46D\?>A2\2446AE2?46\@7\AC@79:=@\C68:DEC2E:@?\2AA=:42E:@?\7@C\724:2=\:?5:42E:@?\b_ah`aca_]9E>=Q E2C86ElQ03=2?<Qm9EEADi^^HHH]AC?6HDH:C6]4@>^?6HD\C6=62D6D^D:DC2>\>65:42=\2??@F?46D\?>A2\2446AE2?46\@7\AC@79:=@\C68:DEC2E:@?\2AA=:42E:@?\7@C\724:2=\:?5:42E:@?\b_ah`aca_]9E>=k^2mk^Am

kAm$~&#rt $:DC2> |65:42= {E5k^Am

kAmk:>8 2=ElQQ DC4lQ9EEADi^^CE]AC?6HDH:C6]4@>^CE]8:7n}6HDxE6>x5lr}fbbebU2>Aj%C2?D>:DD:@?0x5la_ae`_`ha`__!#0}t($0&$!#00000r}fbbebU2>Ajs2E6x5la_ae`_`hQ DEJ=6lQ3@C56Ci_AIj H:5E9i`AIj 96:89Ei`AIjQ ^mk^Am