SHANGHAI, May 6, 2026 /PRNewswire/ -- Alebund Pharmaceuticals (Jiangsu) Limited ("Alebund" or the "Company"), an integrated biopharmaceutical company focusing on developing innovative therapies for the treatment of renal diseases and related chronic conditions, today announced the completion of patient enrollment in the global Phase III pivotal multi-regional clinical trial (RESPOND-2, Study AP301-HP-03) of AP301, a novel fiber-iron-based phosphate binder, for the treatment of hyperphosphatemia. The trial was conducted in the United States and China, led by Dr. Geoffrey A. Block of U.S. Renal Care, with Professor Xiaoqiang Ding, Director of the Department of Nephrology, Zhongshan Hospital, Fudan University serving as the China principal investigator, and enrolled a total of 282 chronic kidney disease ("CKD") patients on maintenance dialysis with hyperphosphatemia — 138 in the U.S. and 144 in China.
As a next-generation fiber-iron-based phosphate binder, AP301 is designed to have a higher phosphate-binding capability, favorable gastrointestinal tolerability, minimal risk of iron overload, and no requirement for chewing before swallowing, with the potential to improve treatment adherence and effectively control hyperphosphatemia.
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